Covance Is Now Labcorp Drug Development
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Acute Toxicity Studies evaluate short-term serious adverse effects after clinical and parenteral administration either as a single dose or in multiple doses during 24 hours.
The test uses two mammalian species, including one non-rodent, and provides the following information:
Data on acute toxicity can predict the outcome in human overdose and supports Phase III clinical trials.
OECD 405/OCSPP 870,24: Acute eye irritation/corrosion
OECD 214: Honeybee (apis mellifera), acute contact toxicity test
OECD 403/OCSPP 870,13: Acute inhalation toxicity
OECD 213: Honeybee (apis mellifera), acute oral toxicity test
OECD 402/OCSPP 870,12: Acute dermal toxicity
About our nonclinical animal research models: We provide the utmost care for our research animals and actively pursue advances in animal welfare. As well as ensuring the highest scientific, ethical and regulatory standards, selection of appropriate animal research models for development research is critical to developing safe and effective treatments, devices and products that protect and save lives. Just as we have ethical committee oversight for human trials, we have ethical committees overseeing all aspects of our global animal care and use programs. All of our core, nonclinical facilities are accredited by AAALAC. Learn more about our commitment to replacing, reusing and refining nonclinical research models.
Labcorp is a leading global life sciences company that includes contract research and developmental services to the pharmaceutical, medical technology, crop protection and chemical industries.
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