Toxicology (TK) / safety sample analysis
Labcorp is a leading global life sciences company that includes contract research and developmental services to the pharmaceutical, medical technology, crop protection and chemical industries.
The objectives of the extended one generation study (OECD 443) are to determine the adverse reproductive and developmental effects that may occur as a result of pre- and postnatal chemical exposure as well as an evaluation of systemic toxicity in pregnant and lactating females and young and adult offspring.
This study evaluates reproductive performance, necropsy, organ weights, sperm motility/counts/morphology, histopathology and ovarian follicle counts of the offspring (F1 generation). The OECD 443 study is primarily conducted in rats via dietary or oral gavage routes of administration.
Toxicology (TK) / safety sample analysis
OECD 505: Residues in livestock
OECD QSAR toolbox
OECD 440: Uterotrophic assay
OPPTS 890,12 Aromatase assay